Do High Protein Diets Increase the Risk of Heart Events and Death?
Higher protein intake was related to higher incidence of MACE in participants over 55 years old, but the association was not evident in their counterparts younger than 55 years old.
Sleep Apnea is a Risk for Parkinson's Disease: Have You Been Tested?
Obstructive sleep apnea (OSA) is associated with many health conditions, including dementia and early mortality. At the KAHN CENTER, we routinely ask about sleep habits and offer easy to use home sleep studies. Every week we make new diagnoses of OSA and refer out for therapy.
Prior studies linking OSA with Parkinson disease (PD) are conflicting, and no studies have examined the influence of continuous positive airway pressure (CPAP), the criterion standard treatment for OSA, on PD risk.
STUDY
This electronic health record (EHR)–based cohort study was conducted among US veterans from January 1, 1999, to December 30, 2022, with mean 5 years. Veterans with PD at the time of exposure or incomplete records were excluded.
RESULTS
A total of 13,737,081 US veterans were screened, and 11,310,411 veterans (1,109,543 female veterans [1o%]) with mean age of 61 years were included in analyses.
Of included veterans, 1,552,505 (14%) had OSA. Veterans with OSA demonstrated 1.61 additional cases of PD at 6 years from diagnosis per 1000 people compared to those without OSA.
Results were confirmed when adjusting for body mass index, vascular comorbidities, psychiatric conditions, and relevant medications and were of greater magnitude in female veterans.
Case numbers were significantly reduced when treated with CPAP early in the disease course.
CONCLUSIONS
OSA appeared to be an independent risk factor for the later development of PD and could be modified by early treatment with CPAP.
Effective screening measures and protocols for consistent adherence to CPAP may have large impacts on brain health.
At the KAHN CENTER, we will continue to offer convenient and accurate home sleep studies to anyone with sleep issues or snoring. Early diagnosis and early treatment will hopefully prevent PD.
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